Wednesday, May 6, 2020
A Romantic And Modernist Perspective - 2041 Words
Kyle D. Brubaker Dr. Vernooy ENG-237-01 11 December 2014 Memory: A Romantic and Modernist Perspective During an age when Britain was producing more writing than perhaps ever before in its history; romantic writers such as Wordsworth and Coleridge place a large emphasis on nature and what impact this construct has on the mind and imagination, while modernist writers such as Hardy, Lawrence, and Yeats attempt to exercise a strong break from tradition. This ideal of ââ¬Å"straying from the packâ⬠creates a sense of bitterness and radical doubt throughout the modernist period, and thus, causes citizens living in this time to carry about their daily activities with doubt and pessimistic attitudes. After examining the literary movements ofâ⬠¦show more contentâ⬠¦One can argue that William Wordsworth believes that memory can be utilized as an anecdote that is able to cure someoneââ¬â¢s pain, while a writer such as Thomas Hardy would disapprove of this Wordsworthian ideal by believing that memory is simply a ââ¬Å"shroud of grayâ⬠(Vernooy). This claim can be supported as true when Wordsworthââ¬â¢s Lines Composed a Few Miles Above Tintern Abbey is examined more closely. Within this piece, Wordsworth states, ââ¬Å"These beauteous forms/Through a long absence, have not been to me/As is a landscape to a blind manââ¬â¢s eye/But oft, in lonely rooms, and ââ¬Ëmid the din/Of towns and cities, I have owed to them/In hours of weariness, sensations sweet (Wordsworth 23-27). Here, Wordsworth provides a detailed description about how nature is able to provide a safe-haven for him in a time when Britainââ¬â¢s cities are looking to industrialize more than ever. By personifying nature during this time of economic crisis, Wordsworth is creating an outlet that aids him in moving forward. Conversely, Thomas Hardy encompasses the idea of nature and memory by almost insulting Wordsworth. For instance, Hardy would argue that one cannot ââ¬Å"sit on the couchâ⬠and rekindle old memories in order to transgress, but instead, one needs to be out and about in order to gather as many physical memories as humanly possible. Within Hardyââ¬â¢s Under the Waterfall, the female persona is attempting to rekindle one of her past memories, which as we all
How Culture Affects Managers Free Essays
How culture affects manager in international organizations. In the last few years globalization has been expanded all around the world in different areas and technology. International organizations have the same effect, organizations that want to have an adventure must require managers or leaderships with general awareness of cultural variables that may affect the business and make this a success or a flop. We will write a custom essay sample on How Culture Affects Managers or any similar topic only for you Order Now Since culture has become one of the main obstacles to standardize decisions and processes in multinational enterprises, a barrier that is sometimes impossible to overcome â⬠¦(XII) After the end of World War II growth of globalization has become widespread, thanks to advances in communication, transportation, technology and trading system. The world is moving into a new millennium and we cannot ignore the importance of international business, and the administration thereof. However adaptation to culture is the most difficult challenge doing international business, this requires an understanding of the different culture, perceptions, stereotypes and values. Only the managers with a wide cultural sensitivity will success. No single nation can be complacent about itself and does not need the assistance and support of other countries, even the riches nations need which lack resources and through global negotiations and agreements supplement their needs and wants. The development of international trade makes countries prosper by leveraging its assets produce better, and then exchanged with other countries, which in turn they produce best. When companies are interested in international trade or looking to diversify markets, they need to negotiate with foreign firms, then countries will be better off. To achieve this they have to resolve conflict or mishaps that may rise when negotiating, because many times one party is not willing to give, so firms need to plan strategies to work to reach an agreement, It is important to know the essential aspects of international negotiation, however culture influences directly in international negotiations, as not all countries negotiate the same way. Aspects such as values, habits, customs, religion, morality, etc. are essential to know, before a firm can have good communication and the n negotiating for a mutually beneficial. Horak, S. (2010). Does The Individualââ¬â¢s Culture Play A Role In The Value Perception Of Members Of Small Multinational Teams?. Business ; Economics Journal, 1-7. The author of this article said How to cite How Culture Affects Managers, Papers
Saturday, April 25, 2020
Materials and Methods free essay sample
Technical grade Diazinon (DZN); O,O-Diethyl O-[4-methyl-6-(propan-2-yl)pyrimidin-2-yl] phosphorothioate (98% purity) was donated from El-Helb, Pesticides and Chemicals, New Damietta, Egypt. It was diluted in corn oil for preparing the required concentrations. Dosing concentrations were freshly prepared during the administration period. Moringa seed oil (MSO) was purchased from Earths Moringa P.O. Box 39503, Los Angeles, CA 90039. Reduced glutathione (GSH), 1-chloro-2, 4-dinitrobenzene, nicotinamide adenine dinucleotide phosphate (NADPH), thiobarbituric acid (TBA), trichloroacetic acid (TCA), H2O2 (33%), ethylenediaminetetraacetic acid (EDTA), reduced glutathione (GSH), 5,5 dithiobis-(2-nitrobenzoic acid (DTNB), potassium fihydrogenphosphate (KH2PO4), butanol and sodium chloride (NaCl) of technical grade used in this study were purchased from Sigma Chemical Company (Saint Louis, USA). Other chemicals were supplied from Merck Led. SRL Pvt., Led., Mumbai, India.2.2. AnimalsTwenty male Albino rats Spragueââ¬âDawley, weighing 180ââ¬â200 g, were supplied from the Animal Breeding House of the Medical Research Institute, Alexandria University, Alexandria, Egypt. Animals were maintained at the animal care facility in the Faculty of Medicine, in plastic cages under controlled temperature (23 à ± 2 oC), 12-h light/dark cycle and 50 à ± 5% relative humidity. We will write a custom essay sample on Materials and Methods or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Water and food were available ad libitum. Rats were acclimatized to the laboratory environment for two weeks prior to the start of the experiments. Animal Care ; Experimental Committee, Alexandria University, Alexandria, Egypt, and all animal procedures were carried out in accordance with the Ethics Committee of the National Research Centre conformed to the Guide for the Care and Use of Laboratory [15]. During the experiments, maximum care was taken to minimize animal suffering and in addition, the number of rats used was kept at minimum.2. 3. Experimental designAfter two weeks of acclimatization, animals were divided into four (n = 5 rats per group) equal groups.â⬠¢ Group 1: Control group; rats were given 1 mL/kg body weight (b,w)/day by gavage for 28 days;â⬠¢ Group 2: DZN group; rats were given DZN 12.50 mg/kg b.w/day (1/100 LD50) by gavage for 28 days. The LD50 and the regime schedule were selected according to the previous study [16,17];â⬠¢ Group 3: MSO group; MSO was given, 200 mg/kg b.w/day, by gavage for 28 days according to the previous study [18];â⬠¢ Group 4: MSO + DZN group; rats were given first with (MSO (200 mg/kg b. w/day) by gavage and after 30 min were given DZN (12.50 mg/kg b.w/day (1/100 LD50) by gavage for 28 days.2.4. Sample collection and preparationThe animals were starved overnight for 12h before blood was collected. Rats were anaesthetized with rats were weighed and anesthetized with sodium pentobarbital (40 mg/kg i. p.), and venous blood samples were collected by direct heart puncture into sterilized vials. Blood samples were allowed set to clot at 4 oC and centrifuged at 2500 g for 10 min. Then 1000 ?l aliquots of serum were placed in microfuge tubes and frozen on dry ice. Labeled bags were placed into freezer at -20 oC until the time of the assay.Livers was removed from rats under anesthesia, after 28 days of treatment and washed with cold saline buffer to remove any clotted blood or tissue debris. Washed livers were immediately stored at ââ¬â 80 oC. To obtain the enzymatic extract, tissues were homogenized in ice-cold 50 mM sodium phosphate buffer (pH 7.0) contains 0.1 mM ethylendiaminetetra-acetic acid (EDTA) to yield 10% (W/V) homogenate. The tissue homogenates were then centrifuged 1500 Xg for 20 minutes at 4 à ºC. The supernatants were kept at ââ¬â 80 à ºC till the time of determination of oxidative/antioxidant parameters.2.5. Serum biomarkersAll serum parameters were determined using a commercial kit in accordance with manufacturers instructions using a spectrophotometer (Shimadzu UV-VIS Recording 2401 PC, Japan). Serum samples were analyzed for total protein by Lowry et al. [19]. Albumin concentration was determined by Doumas et al. [20]. Serum alanine aminotransferase (ALT; EC 2.6. 1.2) and aspartate aminotransferase (AST; EC 2.6.1.1) were determined using commercial kits obtained from Biodiagnostic kit (Cairo, Egypt). The principle reaction of the colorimetric determination of AST or ALT activity is based on the reaction of aspartate or alanine with ?-ketoglutarate to form oxaloacetate or pyruvate hydrazone formed with 2, 4-dinitrophenylhydrazine [21]. Serum alkaline phosphatase (ALP; EC 3. 1.3.1) activity was measured at 405 nm by the formation of para-nitrophenol from para-nitrophenylphosphate as a substrate [22] using commercial kits obtained from Biodiagnostic kit (Cairo, Egypt). Serum lactate dehydrogenase (LDH; EC 1.1.1.27) was determined according to the method of Friedman and Young [23], using kit obtained from Spinreact (Santa Coloma, Spain). Cholesterol and triglycerides was measured according to the method Carr et al. [24] using Biodiagnostic kit (Cairo, Egypt).2.6. Lipid peroxidation assayThe extent of LPO was estimated as the concentration of thiobarbituric acid reactive product malondialdehyde (MDA) by using the method of Ohkawa et al. [25]. MDA concentrations were determined using 1,1,3,3-tetraethoxypropane as standard and expressed as nmol/g liver tissue. 2.7. Antioxidant enzymesCatalase (CAT, EC. 1.11.1.6) activity was measured according to the method described by Aebi by assaying the hydrolysis of H2O2 and the resulting decrease in absorbance at 240 nm over a 3 min period at 25 oC [26]. The activity of CAT enzyme is expressed as U/gm tissue.Glutathione peroxidase (GPx; EC 1.11.1.9) activity was measured using H2O2 as substrate according to the method described by Paglia and Valentine [27]. The reaction was monitored indirectly as the oxidation rate of NADPH at 240 nm for 3 min. Enzyme activity was expressed as U/gm tissue. Superoxide dismutase (SOD, EC 1.15.1.1) activity was determined according to the method described by Marklund and Marklund by assaying the autooxidation and illumination of pyrogallol at 440 nm for 3 min [28].2.8. Reduced glutathione assayReduced GSH estimation was performed by Beutler et al. [29]. Livers were homogenized in 1 ml of 1.1% KCl cooled, then homogenate (100 à µl) was mixed with 750 à µL of precipitate solution (1.67 g glacial meta-phosphoric acid, 0.2 g EDTA and 30 g of NaCl in 100 ml D.W.) and 900 à µl of D. W. Homogenate tissue was centrifuged at 2000g for 15 min to precipitate proteins. Protein-free supernatant (250 à µl) was added to 1ml of Na2HPO4 (0.0 M) and the reaction was initiated by adding 125 à µl of DTNB (6 mM) and the absorbance of 5-thio-nitrobenzoic acid (TNB) formed was measured at 412 nm. The level of GSH was obtained by standard curve and expressed as U/g tissue.2.9. Statistical analysisAll data were expressed as mean à ± standard deviation (SD) and then subjected to one-way analysis of variance followed by Tukeys multiple comparison tests. Values of p
Wednesday, March 18, 2020
The Wright Brothers Make the First Flight
The Wright Brothers Make the First Flight At 10:35 a.m. on December 17, 1903, Orville Wright flew the Flyer for 12 seconds over 120 feet of the ground. This flight, conducted on Kill Devil Hill just outside of Kitty Hawk, North Carolina, was the very first flight by a manned, controlled, heavier-than-air aircraft that flew under its own power. In other words, it was the first flight of an airplane. Who Were the Wright Brothers? Wilbur Wright (1867-1912) and Orville Wright (1871-1948) were brothers who ran both a printing shop and a bicycle shop in Dayton, Ohio. The skills they learned from working on printing presses and bicycles were invaluable in trying to design and build a working airplane. Although the brothers interest in flight had stemmed from a small helicopter toy from their childhood, they didnt begin experimenting with aeronautics until 1899, when Wilbur was 32 and Orville was 28. Wilbur and Orville began by studying aeronautical books, then talked with civil engineers. Next, they built kites. Wing Warping Wilbur and Orville Wright studied the designs and accomplishments of other experimenters but soon realized that no one had yet found a way to control aircraft while in the air. By studiously observing birds in flight, the Wright brothers came up with the concept of wing warping.ââ¬â¹ Wing warping allowed the pilot to control the roll of the plane (horizontal movement) by raising or lowering flaps located along the planes wingtips. For instance, by raising up one flap and lowering the other, the plane would then begin to bank (turn). The Wright brothers tested their ideas using kites and then, in 1900, built their first glider. Testing at Kitty Hawk Needing a place that had regular winds, hills, and sand (to provide a soft landing), the Wright brothers selected Kitty Hawk in North Carolina to conduct their tests. Wilbur and Orville Wright took their glider into the Kill Devil Hills, located just south of Kitty Hawk, and flew it. However, the glider did not do as well as they had hoped. In 1901, they built another glider and tested it, but it too did not work well. Realizing that the problem was in the experimental data they had used from others, they decided to conduct their own experiments. To do so, they went back to Dayton, Ohio and built a small wind tunnel. With the information gained from their own experiments in the wind tunnel, Wilbur and Orville built another glider in 1902. This one, when tested, did exactly what the Wrights expected. Wilbur and Orville Wright had successfully solved the problem of control in flight. Next, they needed to build an aircraft that had both control and motorized power. The Wright Brothers Build the Flyer The Wrights needed an engine that would be powerful enough to lift a plane from the ground, but not weigh it down significantly. After contacting a number of engine manufacturers and not finding any engines light enough for their task, the Wrights realized that in order to get an engine with the specifications they needed, they must design and build their own. While the Wilbur and Orville Wright designed the engine, it was the clever and able Charlie Taylor, a machinist who worked with the Wright brothers in their bicycle shop, who built it carefully crafting each individual, unique piece. With little experience working with engines, the three men managed to put together a 4-cylinder, 8 horsepower, gasoline engine that weighed 152 pounds in just six weeks. However, after some testing, the engine block cracked. It took another two months to make a new one, but this time, the engine had a whopping 12 horsepower. Another engineering struggle was determining the shape and size of the propellers. Orville and Wilbur would constantly discuss the intricacies of their engineering problems. Although they hoped to find solutions in nautical engineering books, they ultimately discovered their own answers through trial, error, and lots of discussion. When the engine was completed and the two propellers created, Wilbur and Orville placed these into their newly built, 21-foot long, spruce-and-ash framed Flyer. With the finished product weighing 605 pounds, the Wright brothers hoped that the motor would be strong enough to lift the plane. It was time to test their new, controlled, motorized aircraft. The December 14, 1903 Test Wilbur and Orville Wright traveled to Kitty Hawk in September 1903. Technical difficulties and weather problems delayed the first test until December 14, 1903. Wilbur and Orville flipped a coin to see who would get to make the first test flight and Wilbur won. However, there wasnt enough wind that day, so the Wright brothers took the Flyer up to a hill and flew it. Although it did take flight, it crashed at the end and needed a couple days to repair. Nothing definitive was gained from this flight since the Flyer had taken off from a hill. The First Flight at Kitty Hawk On December 17, 1903, the Flyer was fixed and ready to go. The weather was cold and windy, with winds reported around 20 to 27 miles per hour. The brothers tried to wait until the weather improved but by 10 a.m. it had not, so they decided to try a flight anyway. The two brothers, plus several helpers, set up the 60-foot monorail track that helped keep the Flyer in line for lift-off. Since Wilbur had won the coin toss on December 14,à it was Orvilles turn to pilot. Orvilleà clambered onto the Flyer, laying flat on his tummy on the middle of the bottom wing. The biplane, which had a 40-foot 4-inch wingspan, was ready to go. At 10:35 a.m. the Flyer started off with Orville as pilot and Wilbur running along the right side, holding onto the lower wing to help stabilize the plane. Around 40 feet along the track, the Flyer took flight, staying in the air for 12 seconds and traveling 120 feet from liftoff. They had done it. They had made the very first flight with a manned, controlled, powered, heavier-than-air aircraft. Three More Flights That Day The men were excited about their triumph but they were not done for the day. They went back inside to warm up by a fire and then went back outside for three more flights. The fourth and final flight proved their best. During that last flight, Wilbur piloted the Flyer for 59 seconds over 852 feet. After the fourth test flight, a strong gust of wind blew the Flyer over, making it tumble and breaking it so severely that it would never be flown again.à After Kitty Hawk Over the next several years, the Wright Brothers would continue perfecting their airplane designs but would suffer a major setback in 1908 when they were involved in the first fatal airplane crash. In this crash, Orville Wright was severely injured butà passenger Lieutenant Thomas Selfridge died. Four years later, having recently returned from a six-month trip to Europe for business, Wilbur Wright became ill with typhoid fever. Wilbur never recovered, passing away on May 30, 1912, at the age of 45. Orville Wright continued to fly for the next six years, making daring stunts and setting speed records, stopping only when aches left over from his 1908 crash would no longer let him fly. Over the next three decades, Orville kept busy continuing scientific research, making public appearances, and battling lawsuits. He lived long enough to witness the historic flights of great aviators such as Charles Lindbergh and Amelia Earhart as well as recognize theà important roles that planes played in World War I and World War II. On January 30, 1948, Orville Wright died at age 77 of a massive heart attack.
Sunday, March 1, 2020
The History of the Drug Krokodil
The History of the Drug Krokodil Krokodil is the street name for desomorphine an opiate-like drug similar to and a substitute for heroin used by addicts. Krokodil or desomorphine began its history as a patented drug. US patent 1980972 was issued to chemist, Lyndon Frederick Small for a Morphine Derivative and Processes on November 13, 1934. The drug was briefly manufactured and marketed by the Swiss pharmaceutical company Roche under the brand name of Permonid but was abandoned as a commercial product for its short shelf life and highly addictive nature. In the early 2000s, the drug resurfaced in Russia as krokodil, a home-brewed heroin substitute that takes about thirty minutes to manufacture from codeine pills and other substances. The home brewing of this drug includes the inclusion of impurities and toxic substances that have lead to some horrific consequences for users. Krokodil (Russian for crocodile) is named after one of the drugs major side effect, the greenish and scaly appearance of the damaged and rotting skin of users. Take one look at this Huffington Post video report and youll be quickly convinced never to try this drug. If You Dont Want It - Recycled Patents Many illicit street drugs (and even semi-legal ones) have had their origins in legitimate research done by pharmaceutical companies, research that has even resulted in patents being issued. For example, organic chemist John Huffman was the unwitting inventor of a synthetic version of marijuana. A few enterprising individuals read John Huffmans research on synthetic cannabinoids and began manufacturing and selling synthetic marijuana products such as Spice. These products were legal for a short spell of time, however, in most places they are no longer legal. Another popular street drug is MDMA or Molly as it is now called. The original formula for Molly was patented in 1913 by Merck, a German chemical company. Molly was intended to be a diet pill, however, Merck decided against marketing the drug and abandoned it. MDMA was made illegal in 1983, seventy years after it was originally invented. Heroin was once a registered trademark belonging to Bayer, the same folks that invented aspirin. A method of manufacturing heroin from the opium poppy was developed in 1874, as a substitute for morphine, and believe or not was used as a cough suppressant. The mind-bending psychedelic drug LSD was first synthesized on November 16, 1938 by Swiss chemist Albert Hofmann while working for Sandoz Laboratories in Switzerland. However, it was a few years before Albert Hofmann realized what he had invented. Until 1914, cocaine was legal and even an ingredient in the soft drink Coca-Cola. The method of manufacturing cocaine from the coca leaf was invented in the 1860s. Lyndon Frederick Small 1897- 1957 A 1931 Time Magazine article discusses the work of Frederick Small Lyndon in relation to the growing opiate epidemic in the United States. ....the Bureau of Social Hygiene gave the National Research Council funds for a study of drug addiction and the invention of a drug which would do for medicine everything which the habit-forming drugs do, yet not cause habit itself. Such a harmless, beneficial drug would make the manufacture of the baneful drugs needless. Then they could be completely suppressed. Council discovered Dr. Lyndon Frederick Small, just returned from two years of study in Europe, at the University of Virginia and financed a special laboratory for him. Out of a coal tar product called phenanthrene he has synthesized several drugs which closely resemble the chemical structure and physiological action of morphine. He sends them to Professor Charles Wallis Edmunds of the University of Michigan who tests them on animals. The two are confident that within perhaps a few months they will have an authentic drug which will not make, as morphine, heroin and opium do, pasty-faced, emaciated, depraved liars, out of its users.
Friday, February 14, 2020
Error Simulation Enviroment For The Dicode Pulse Position Modulation Essay
Error Simulation Enviroment For The Dicode Pulse Position Modulation - Essay Example The number of erasure error symbols that is erased is within the capacity of the decoder in his recovery of the original data. In this test design, the number of erasure error symbols must be less or equal to 8 symbols per codeword. Figures (7.2) & (7.3) show the system input/output signals. Figure (7.2) shows the performance of the system when the number of erasure symbols equals 8 per codeword, while the figure (7.3) displays the system signals when the number of erasure symbols equals 5. In these figures, the fail output signal is logic 0. This means that the system has successfully decoded the original codeword. We can add or delete erasures by updating lines 294 and 295 inside the code. The number of erasure error symbols that is erased is greater than the capacity of the decoder to recover the original data. In this test design, the number of erasure symbols is greater than 8 symbols per codeword. Figure (7.4) shows the system input/output signals when the number of erasure sym bols equals 9 per codeword. In this figure, the fail output signal is logic 1, which means that the system has failed to decode the original codeword. We can add or delete erasures by updating lines 294 and 295. A VHDL test bench program Appendix ( ) has been built to provide an environment where errors can be injected into the system. According to equation (6.7), the designed system has the ability to correct up to 4 erasure errors only. Above this number, the system will fail to decode the original message.
Saturday, February 1, 2020
Research Proposal Essay Example | Topics and Well Written Essays - 4000 words
Research Proposal - Essay Example Information on the prevalence of obesity within the military is limited and usually relies on reported data on height and weight or on unrepresented smaller samples. According to Rona et al (2010), BMI is the usual indicator to assess overweight and obesity among army personnel but its validity is questionable because some people may have huge bodies but not obese. As such, in this proposal the author will make reasoned judgements and draw conclusions from these findings along with evaluating the significance of the assessment criteria used in monitoring obesity. Furthermore, the proposal also seeks to highlight the reason why the prevalence rate of obesity at the time of recruitment is low and subsequently increases over the years. The problem of obesity affects the military personnel in many ways. According to the World Health Organisation (2000) ââ¬ËObesity is diagnosed as having a body mass index of 25 and overââ¬â¢. Thus the Ministry of Defence has adopted the WHO BMI char t and all personnel have their measurements taken and calculated as above and classified according to this chart. This will be further reviewed within this proposal. CONCLUSION Prevalence rates of obesity from this study should be viewed with caution as the sample studied is not representative of the UK Armed Forces. The true percentage of obesity could be higher since the sample is drawn from a small number of people. This research proposal aims to use a quantitative research method to evaluate the use of BMI and waist circumference to monitor obesity levels within the RAF. In turn this research proposal will highlight how BMI and waist circumference monitoring negatively reflects the obesity statistics in RAF personnel. Consequently the results of this research proposal will be used to: Highlight the importance of accurate measurements to assess obesity. In turn it will provide evidence to HQ Air to rethink current policy and perhaps adopt a tri service approach to tackling this p roblem in the future. INTRODUCTION Preventing obesity is essential within the military, not only to decrease the risk of cardiovascular disease and other chronic conditions (Ogden, et al 2007) but also to increase fitness and operational preparedness. This is essential since it improves their performance and physical fitness. The prevalence of obesity in the United Kingdom Armed Forces has not previously been monitored. Military personnel undergo annual health examination dependent on trade/branch (Joint Service Publication, 346 Chapter 2, 2008 will be hereafter referred to as JSP). Despite these examinations, there appears to be a requirement for a more robust information system to estimate obesity within the military (Rona et al, 2011). According to the JSP 346 the assessment process appears to rely heavily on how healthcare staff interprets height and weight measurements in order to calculate Body Mass Index (BMI). BMI provides the most useful population-level measure of obesity as it is the same for both sexes and for all ages of adults (WHO, 2012). The notion that BMI should be used when assessing obesity is backed by US research (Rona, 2012). However, the drawback of this method is that an increase in BMI may not necessarily mean that a person is obese since military personnel have greater muscle mass than ordinary citizens. In 2006, the National Institute for Health and Clinical
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